many Member (with the permission of the federal government, seen that the Comprehensive Drug Abuse Prevention and Control Act 1970 places the cannabis in the table more restrictive) to allow patients undergoing chemotherapy for cancer to use hemp. Last September Grinspoon took part in the conference on "therapeutic hemp: science and law", organised in Rome by Forum drugs, and on that occasion to know interviewed him. Professor Grinspoon, what is true on the therapeutic properties of hemp? "It was used as a medicine for thousands of years. The first testimony dates back to 5,000 years ago, in one written of the reign of the Emperor China Chen Nun, that the recommended for malaria and rheumatic pains. When I made my first study, in 1967, I found about one hundred paper on therapeutic uses of cannabis in western medicine between 1840 and 1900. Was indicated as stimulating appetite, muscle relaxant, analgesic, sedative, anticonvulsant and to treat the dependence from opium. He was a professor at the faculty of medicine of Calcutta, William Brooke O'Shaughnessy, the first Western physician to notice of its curative properties. In the first half of the Nineteenth Century, after it has been tested on animals, began to use it with hydrophobic patients, or suffering from rheumatism, epilepsy or infected with tetanus. The decline of its medical use are recorded already from 1890, with the discovery of aspirin and then of chloral hydrate and barbiturates. The lack of interest for the study of the analgesic properties is instead linked to the diffusion of the opiates and the invention of the hypodermic syringe that has allowed the administration of analgesics quick action intravenously. In 1941, finally, an indirect consequence of the Marijuana Tax Act of 1937, cannabis was excluded from the United States Pharmacopoeia. Personally, the stories of many clinical cases have convinced me that this is a miraculous substance to the equal of the penicillin of the XXI century. Works in alleviating the symptoms of chemotherapy against cancer, multiple sclerosis, osteoarthritis, glaucoma, AIDS and depression, in addition to the symptoms of diseases less common as Crohn's disease, diabetic gastroparesis and disorders from post-traumatic stress". It is mostly anecdotal evidence, however, not recognized in full by the scientific world… "It is true, there are no research with control groups and double-blind to know the percentage of cases in which marijuana can be effective for a certain degree of disturbance. But in my opinion not serve studies so costly. Its use is based on the reports of individual cases would be a problem if cannabis was dangerous. But the research carried out in all these years have demonstrated that it is more secure than most prescription drugs, has fewer side effects and creates much less dependence of other substances in use today. I am not sure that for demonstrating the efficacy and harmlessness agree to apply the protocol of the Food and Drug Administration. In general, in fact, pharmaceutical companies to see approved their products must submit them to a risk analysis- Benefits: a very expensive operation that companies argue only if they can fall of expenditure over the twenty years of duration of the patent. But no company is concerned to conduct research on a plant that cannot be patented. And then, I wonder, why spend money to understand at the end what we already know? Having regard to the low risks linked to the medical use of hemp, should be made available even if only a few patients could benefit from it. In short, the risk is so low that prohibit the use waiting to evaluate it does not make sense." Excludes that have toxic effects? "I have never found proof, nor have you ever recorded a case of death by overdose from marijuana. In the entire pharmacopoeia you can not say the same of any other drug. It is certainly less toxic most of the medicines. Take aspirin: is considered safe and little harmful, and yet in the United States each year from 1,000 to 2,000 people die for swallowing and 74 thousand are hospitalized for side effects of anti-inflammatory. In fact, what worries most is the respiratory damage from the smoke, but this can be solved by resorting to devices for vaporization which separate the particles of matter present in the smoke of marijuana by its active principles, cannabinoids". In 2006 the British government has approved the sale of the Sativex, drug for the treatment of neuropathic pain in patients with multiple sclerosis. She however is a supporter of greater effectiveness of hemp smoked with respect to the synthetic derivatives. Why? "The development of single cannabinoids, synthetic cannabinoids, is the way in which an attempt is made to resolve the problem of making available the medical properties of cannabis and at the same time a ban to who makes a playful use. This "farmaceutizzazione" however does not render ever obsolete the smoked cannabis. Let us take the case of the dronabinol, approved in 1985 by the Food and Drug Administration with the name of Marinol, for the treatment of nausea and vomiting from chemotherapy: Most patients continued to find much more useful the grass. In fact, for certain patients some derivatives of cannabis may have advantages over the smoked marijuana or ingested. For example, the cannabidiol can be more effective as anxiolytic drug and as anticonvulsant when is not taken together to THC, that sometimes generates anxiety. But I do not believe that these derivatives can be more useful of cannabis". What is the rule with the dosage? "The advantage of administration of cannabis through the lungs is the rapidity with which it takes effect, which allows patients to calibrate the dose. This is not possible by taking cannabis in pills: it takes more time because the therapeutic effect is manifested. With the Sativex, GW Pharmaceuticals are trying to develop products and systems of administration that would bypass the two most common concerns: the smoke and the effects psychoactive (the so-called "high"). The drug must many Member (with the permission of the federal government, seen that the Comprehensive Drug Abuse Prevention and Control Act 1970 places the cannabis in the table more restrictive) to allow patients undergoing chemotherapy for cancer to use hemp. Last September Grinspoon took part in the conference on "therapeutic hemp: science and law", organised in Rome by Forum drugs, and on that occasion to know interviewed him. Professor Grinspoon, what is true on the therapeutic properties of hemp? "It was used as a medicine for thousands of years. The first testimony dates back to 5,000 years ago, in one written of the reign of the Emperor China Chen Nun, that the recommended for malaria and rheumatic pains. When I made my first study, in 1967, I found about one hundred paper on therapeutic uses of cannabis in western medicine between 1840 and 1900. Was indicated as stimulating appetite, muscle relaxant, analgesic, sedative, anticonvulsant and to treat the dependence from opium. He was a professor at the faculty of medicine of Calcutta, William Brooke O'Shaughnessy, the first Western physician to notice of its curative properties. In the first half of the Nineteenth Century, after it has been tested on animals, began to use it with hydrophobic patients, or suffering from rheumatism, epilepsy or infected with tetanus. The decline of its medical use are recorded already from 1890, with the discovery of aspirin and then of chloral hydrate and barbiturates. The lack of interest for the study of the analgesic properties is instead linked to the diffusion of the opiates and the invention of the hypodermic syringe that has allowed the administration of analgesics quick action intravenously. In 1941, finally, an indirect consequence of the Marijuana Tax Act of 1937, cannabis was excluded from the United States Pharmacopoeia. Personally, the stories of many clinical cases have convinced me that this is a miraculous substance to the equal of the penicillin of the XXI century. Works in alleviating the symptoms of chemotherapy against cancer, multiple sclerosis, osteoarthritis, glaucoma, AIDS and depression, in addition to the symptoms of diseases less common as Crohn's disease, diabetic gastroparesis and disorders from post-traumatic stress". It is mostly anecdotal evidence, however, not recognized in full by the scientific world… "It is true, there are no research with control groups and double-blind to know the percentage of cases in which marijuana can be effective for a certain degree of disturbance. But in my opinion not serve studies so costly. Its use is based on the reports of individual cases would be a problem if cannabis was dangerous. But the research carried out in all these years have demonstrated that it is more secure than most prescription drugs, has fewer side effects and creates much less dependence of other substances in use today. I am not sure that for demonstrating the efficacy and harmlessness agree to apply the protocol of the Food and Drug Administration. In general, in fact, pharmaceutical companies to see approved their products must submit them to a risk analysis- Benefits: a very expensive operation that companies argue only if they can fall of expenditure over the twenty years of duration of the patent. But no company is concerned to conduct research on a plant that cannot be patented. And then, I wonder, why spend money to understand at the end what we already know? Having regard to the low risks linked to the medical use of hemp, should be made available even if only a few patients could benefit from it. In short, the risk is so low that prohibit the use waiting to evaluate it does not make sense." Excludes that have toxic effects? "I have never found proof, nor have you ever recorded a case of death by overdose from marijuana. In the entire pharmacopoeia you can not say the same of any other drug. It is certainly less toxic most of the medicines. Take aspirin: is considered safe and little harmful, and yet in the United States each year from 1,000 to 2,000 people die for swallowing and 74 thousand are hospitalized for side effects of anti-inflammatory. In fact, what worries most is the respiratory damage from the smoke, but this can be solved by resorting to devices for vaporization which separate the particles of matter present in the smoke of marijuana by its active principles, cannabinoids". In 2006 the British government has approved the sale of the Sativex, drug for the treatment of neuropathic pain in patients with multiple sclerosis. She however is a supporter of greater effectiveness of hemp smoked with respect to the synthetic derivatives. Why? "The development of single cannabinoids, synthetic cannabinoids, is the way in which an attempt is made to resolve the problem of making available the medical properties of cannabis and at the same time a ban to who makes a playful use. This "farmaceutizzazione" however does not render ever obsolete the smoked cannabis. Let us take the case of the dronabinol, approved in 1985 by the Food and Drug Administration with the name of Marinol, for the treatment of nausea and vomiting from chemotherapy: Most patients continued to find much more useful the grass. In fact, for certain patients some derivatives of cannabis may have advantages over the smoked marijuana or ingested. For example, the cannabidiol can be more effective as anxiolytic drug and as anticonvulsant when is not taken together to THC, that sometimes generates anxiety. But I do not believe that these derivatives can be more useful of cannabis". What is the rule with the dosage? "The advantage of administration of cannabis through the lungs is the rapidity with which it takes effect, which allows patients to calibrate the dose. This is not possible by taking cannabis in pills: it takes more time because the therapeutic effect is manifested. With the Sativex, GW Pharmaceuticals are trying to develop products and systems of administration that would bypass the two most common concerns: the smoke and the effects psychoactive (the so-called "high"). The drug must many Member (with the permission of the federal government, seen that the Comprehensive Drug Abuse Prevention and Control Act 1970 places the cannabis in the table more restrictive) to allow patients undergoing chemotherapy for cancer to use hemp. Last September Grinspoon took part in the conference on "therapeutic hemp: science and law", organised in Rome by Forum drugs, and on that occasion to know interviewed him. Professor Grinspoon, what is true on the therapeutic properties of hemp? "It was used as a medicine for thousands of years. The first testimony dates back to 5,000 years ago, in one written of the reign of the Emperor China Chen Nun, that the recommended for malaria and rheumatic pains. When I made my first study, in 1967, I found about one hundred paper on therapeutic uses of cannabis in western medicine between 1840 and 1900. Was indicated as stimulating appetite, muscle relaxant, analgesic, sedative, anticonvulsant and to treat the dependence from opium. He was a professor at the faculty of medicine of Calcutta, William Brooke O'Shaughnessy, the first Western physician to notice of its curative properties. In the first half of the Nineteenth Century, after it has been tested on animals, began to use it with hydrophobic patients, or suffering from rheumatism, epilepsy or infected with tetanus. The decline of its medical use are recorded already from 1890, with the discovery of aspirin and then of chloral hydrate and barbiturates. The lack of interest for the study of the analgesic properties is instead linked to the diffusion of the opiates and the invention of the hypodermic syringe that has allowed the administration of analgesics quick action intravenously. In 1941, finally, an indirect consequence of the Marijuana Tax Act of 1937, cannabis was excluded from the United States Pharmacopoeia. Personally, the stories of many clinical cases have convinced me that this is a miraculous substance to the equal of the penicillin of the XXI century. Works in alleviating the symptoms of chemotherapy against cancer, multiple sclerosis, osteoarthritis, glaucoma, AIDS and depression, in addition to the symptoms of diseases less common as Crohn's disease, diabetic gastroparesis and disorders from post-traumatic stress". It is mostly anecdotal evidence, however, not recognized in full by the scientific world… "It is true, there are no research with control groups and double-blind to know the percentage of cases in which marijuana can be effective for a certain degree of disturbance. But in my opinion not serve studies so costly. Its use is based on the reports of individual cases would be a problem if cannabis was dangerous. But the research carried out in all these years have demonstrated that it is more secure than most prescription drugs, has fewer side effects and creates much less dependence of other substances in use today. I am not sure that for demonstrating the efficacy and harmlessness agree to apply the protocol of the Food and Drug Administration. In general, in fact, pharmaceutical companies to see approved their products must submit them to a risk analysis- Benefits: a very expensive operation that companies argue only if they can fall of expenditure over the twenty years of duration of the patent. But no company is concerned to conduct research on a plant that cannot be patented. And then, I wonder, why spend money to understand at the end what we already know? Having regard to the low risks linked to the medical use of hemp, should be made available even if only a few patients could benefit from it. In short, the risk is so low that prohibit the use waiting to evaluate it does not make sense." Excludes that have toxic effects? "I have never found proof, nor have you ever recorded a case of death by overdose from marijuana. In the entire pharmacopoeia you can not say the same of any other drug. It is certainly less toxic most of the medicines. Take aspirin: is considered safe and little harmful, and yet in the United States each year from 1,000 to 2,000 people die for swallowing and 74 thousand are hospitalized for side effects of anti-inflammatory. In fact, what worries most is the respiratory damage from the smoke, but this can be solved by resorting to devices for vaporization which separate the particles of matter present in the smoke of marijuana by its active principles, cannabinoids". In 2006 the British government has approved the sale of the Sativex, drug for the treatment of neuropathic pain in patients with multiple sclerosis. She however is a supporter of greater effectiveness of hemp smoked with respect to the synthetic derivatives. Why? "The development of single cannabinoids, synthetic cannabinoids, is the way in which an attempt is made to resolve the problem of making available the medical properties of cannabis and at the same time a ban to who makes a playful use. This "farmaceutizzazione" however does not render ever obsolete the smoked cannabis. Let us take the case of the dronabinol, approved in 1985 by the Food and Drug Administration with the name of Marinol, for the treatment of nausea and vomiting from chemotherapy: Most patients continued to find much more useful the grass. In fact, for certain patients some derivatives of cannabis may have advantages over the smoked marijuana or ingested. For example, the cannabidiol can be more effective as anxiolytic drug and as anticonvulsant when is not taken together to THC, that sometimes generates anxiety. But I do not believe that these derivatives can be more useful of cannabis". What is the rule with the dosage? "The advantage of administration of cannabis through the lungs is the rapidity with which it takes effect, which allows patients to calibrate the dose. This is not possible by taking cannabis in pills: it takes more time because the therapeutic effect is manifested. With the Sativex, GW Pharmaceuticals are trying to develop products and systems of administration that would bypass the two most common concerns: the smoke and the effects psychoactive (the so-called "high"). The drug must many Member (with the permission of the federal government, seen that the Comprehensive Drug Abuse Prevention and Control Act 1970 places the cannabis in the table more restrictive) to allow patients undergoing chemotherapy for cancer to use hemp. Last September Grinspoon took part in the conference on "therapeutic hemp: science and law", organised in Rome by Forum drugs, and on that occasion to know interviewed him. Professor Grinspoon, what is true on the therapeutic properties of hemp? "It was used as a medicine for thousands of years. The first testimony dates back to 5,000 years ago, in one written of the reign of the Emperor China Chen Nun, that the recommended for malaria and rheumatic pains. When I made my first study, in 1967, I found about one hundred paper on therapeutic uses of cannabis in western medicine between 1840 and 1900. Was indicated as stimulating appetite, muscle relaxant, analgesic, sedative, anticonvulsant and to treat the dependence from opium. He was a professor at the faculty of medicine of Calcutta, William Brooke O'Shaughnessy, the first Western physician to notice of its curative properties. In the first half of the Nineteenth Century, after it has been tested on animals, began to use it with hydrophobic patients, or suffering from rheumatism, epilepsy or infected with tetanus. The decline of its medical use are recorded already from 1890, with the discovery of aspirin and then of chloral hydrate and barbiturates. The lack of interest for the study of the analgesic properties is instead linked to the diffusion of the opiates and the invention of the hypodermic syringe that has allowed the administration of analgesics quick action intravenously. In 1941, finally, an indirect consequence of the Marijuana Tax Act of 1937, cannabis was excluded from the United States Pharmacopoeia. Personally, the stories of many clinical cases have convinced me that this is a miraculous substance to the equal of the penicillin of the XXI century. Works in alleviating the symptoms of chemotherapy against cancer, multiple sclerosis, osteoarthritis, glaucoma, AIDS and depression, in addition to the symptoms of diseases less common as Crohn's disease, diabetic gastroparesis and disorders from post-traumatic stress". It is mostly anecdotal evidence, however, not recognized in full by the scientific world… "It is true, there are no research with control groups and double-blind to know the percentage of cases in which marijuana can be effective for a certain degree of disturbance. But in my opinion not serve studies so costly. Its use is based on the reports of individual cases would be a problem if cannabis was dangerous. But the research carried out in all these years have demonstrated that it is more secure than most prescription drugs, has fewer side effects and creates much less dependence of other substances in use today. I am not sure that for demonstrating the efficacy and harmlessness agree to apply the protocol of the Food and Drug Administration. In general, in fact, pharmaceutical companies to see approved their products must submit them to a risk analysis- Benefits: a very expensive operation that companies argue only if they can fall of expenditure over the twenty years of duration of the patent. But no company is concerned to conduct research on a plant that cannot be patented. And then, I wonder, why spend money to understand at the end what we already know? Having regard to the low risks linked to the medical use of hemp, should be made available even if only a few patients could benefit from it. In short, the risk is so low that prohibit the use waiting to evaluate it does not make sense." Excludes that have toxic effects? "I have never found proof, nor have you ever recorded a case of death by overdose from marijuana. In the entire pharmacopoeia you can not say the same of any other drug. It is certainly less toxic most of the medicines. Take aspirin: is considered safe and little harmful, and yet in the United States each year from 1,000 to 2,000 people die for swallowing and 74 thousand are hospitalized for side effects of anti-inflammatory. In fact, what worries most is the respiratory damage from the smoke, but this can be solved by resorting to devices for vaporization which separate the particles of matter present in the smoke of marijuana by its active principles, cannabinoids". In 2006 the British government has approved the sale of the Sativex, drug for the treatment of neuropathic pain in patients with multiple sclerosis. She however is a supporter of greater effectiveness of hemp smoked with respect to the synthetic derivatives. Why? "The development of single cannabinoids, synthetic cannabinoids, is the way in which an attempt is made to resolve the problem of making available the medical properties of cannabis and at the same time a ban to who makes a playful use. This "farmaceutizzazione" however does not render ever obsolete the smoked cannabis. Let us take the case of the dronabinol, approved in 1985 by the Food and Drug Administration with the name of Marinol, for the treatment of nausea and vomiting from chemotherapy: Most patients continued to find much more useful the grass. In fact, for certain patients some derivatives of cannabis may have advantages over the smoked marijuana or ingested. For example, the cannabidiol can be more effective as anxiolytic drug and as anticonvulsant when is not taken together to THC, that sometimes generates anxiety. But I do not believe that these derivatives can be more useful of cannabis". What is the rule with the dosage? "The advantage of administration of cannabis through the lungs is the rapidity with which it takes effect, which allows patients to calibrate the dose. This is not possible by taking cannabis in pills: it takes more time because the therapeutic effect is manifested. With the Sativex, GW Pharmaceuticals are trying to develop products and systems of administration that would bypass the two most common concerns: the smoke and the effects psychoactive (the so-called "high"). The drug must